Isolation , Partial Characterization of a Flavone From Sudanese Terminalia brownii (Comretaceae) Root and Biological Activity of Ethanol Extract

  • Mohamed Abdel Karim Sudan University of Science and Technology
  • Ibrahim, M Sudan University of Science and Technology
  • Mohamed,S. Sudan University of Science and Technology
  • Ayda,Y Najran University
DOI: https://doi.org/10.53555/bs.v5i8.3179
Keywords: Terminalia brownii, Isolation, Flavonoid, Antimicrobial Activity, Antioxidant activity

Abstract

Terminalia brownii is widely used in African system of medicine as a natural remedy for cough, tonsillitis, typhoid, tooth-ache, snake bite and rheumatic pain . Phytochemical screening of Terminalia brownii root revealed the presence of flavonoids , alkaloids,steroids, tannins, terpenes, saponins and coumarins. A flavonoid - compound I- was isolated from the ethanol extract by  paper chromatography and its structure was partially characterized via some spectral data ( UV and 1HNMR).In the agar diffusion bioassay,the ethanol extract showed significant activity against Pseudomonas aeruginosa and Staphylococcus aureus. It  exhibited moderate activity against Escherichia coli and the yeast Candida albicans . It also showed moderate free radical scavenging capacity  against stable DPPH radicals.

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Author Biographies

Mohamed Abdel Karim, Sudan University of Science and Technology

Faculty of Science, Sudan University of Science and Technology

Ibrahim, M , Sudan University of Science and Technology

Faculty of Science, Sudan University of Science and Technology

Mohamed,S., Sudan University of Science and Technology

Faculty of Science, Sudan University of Science and Technology

Ayda,Y, Najran University

Najran University, Faculty of Science and Arts(Saudi Arabia)

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Published
2019-08-30
How to Cite
Karim, M. A., Ibrahim, M, Mohamed,S., & Ayda,Y. (2019). Isolation , Partial Characterization of a Flavone From Sudanese Terminalia brownii (Comretaceae) Root and Biological Activity of Ethanol Extract. IJRDO - JOURNAL OF BIOLOGICAL SCIENCE, 5(8), 01-08. https://doi.org/10.53555/bs.v5i8.3179
Issue
Vol. 5 No. 8 (2019): IJRDO - Journal Of Biological Science | ISSN: 2455-7676
Section
Articles

Copyright (c) 2019 IJRDO - Journal of Biological Science (ISSN: 2455-7676)

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